Compositional Data Analysis of Periodontal Disease Microbial Communities

Microbial Etiology of Periodontal Disease – Mini Review

The periodontal disease is a chronic, degenerative disease which is localised on the gingiva, periodontal ligament, cementum and alveolar bone. The main etiological factor is oral biofilm with microorganisms. The search for the pathogens of periodontal diseases has been underway for more than 100 years, and continues up today. The currently recognized key Gram negative periodontopathogens inclu...

Subgingival microbial profiles in refractory periodontal disease.

BACKGROUND/AIM The purpose of the present investigation was to examine subgingival microbial profiles associated with refractory periodontitis and to seek such profiles in periodontally healthy, periodontally well-maintained elder and untreated periodontitis subjects. METHODS 36 subjects were defined as refractory on the basis of further attachment loss after scaling and root planing, surgery...

Multi-omics Analysis of Periodontal Pocket Microbial Communities Pre- and Posttreatment

Periodontitis is a polymicrobial infectious disease that causes breakdown of the periodontal ligament and alveolar bone. We employed a meta-omics approach that included microbial 16S rRNA amplicon sequencing, shotgun metagenomics, and tandem mass spectrometry to analyze sub- and supragingival biofilms in adults with chronic periodontitis pre- and posttreatment with 0.25% sodium hypochlorite. Mi...

Comparative molecular analysis of endoevaporitic microbial communities.

A phylogenetic comparison of microbial communities in hypersaline evaporites was conducted on crusts from Guerrero Negro, Mexico, and Lindsey Lake, New Mexico, using culture-independent rRNA gene sequence analysis. Many sequences were shared between evaporites, which suggests that similar environments select for specific microbial lineages from a global metacommunity.

Running head : Coral microbial communities and disease